A diarylamine derived from anthranilic acid inhibits ZIKV replication
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چکیده
منابع مشابه
Enzymatic Formation of Catechol from Anthranilic Acid.
Anthranilic acid is known to be formed from kynurenine in animals and microorganisms (3-6) and to be degraded by cell-free extracts of a Pseudomonas species adapted to L-tryptophan (7). Catechol has been postulated as an intermediate in the catabolism of anthranilic acid on the basis of experiments utilizing sequential enzyme induction (8). Several groups of investigators have recently succeede...
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Anthranilic acid is known to be formed from kynurenine in animals and microorganisms (3-6) and to be degraded by cell-free extracts of a Pseudomonas species adapted to L-tryptophan (7). Catechol has been postulated as an intermediate in the catabolism of anthranilic acid on the basis of experiments utilizing sequential enzyme induction (8). Several groups of investigators have recently succeede...
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A new anthranilic acid hydroxylase which catalyzes the conversion of anthranilic acid to 2,3-dihydroxybenzoic acid, has been partially purified from crude extracts of the mycelial felts of Aspergillus niger, grown in the presence of anthranilic acid. Neither 3-hydroxyanthranilic acid nor salicylic acid is an intermediate in this conversion. The enzyme is stabilized by glutathione and requires s...
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Five new anthranilic acid derivatives, penipacids A-E (1-5), together with one known analogue (6), which was previously synthesized, were characterized from the ethyl acetate extract of the marine sediment-derived fungus Penicillium paneum SD-44. Their structures were elucidated mainly by extensive NMR spectroscopic and mass spectrometric analysis. The cytotoxicity and antimicrobial activity of...
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Laggera pterodonta (DC.) Benth. is a traditional Chinese medicine. The previous study revealed that the crude extracts of this herb could inhibit influenza virus infection, but its anti-influenza components and underlying mechanism of action remain unknown. Column chromatography was performed to isolate components from the plant. Activity against influenza virus of the compound was determined b...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-54169-z